<PAGE>
 
             As filed with the Securities and Exchange Commission
                               on April 23, 1998
 
                                              Registration No. 333-_____
================================================================================

                      SECURITIES AND EXCHANGE COMMISSION
                            Washington, D.C. 20549

                                   FORM S-8

                         REGISTRATION STATEMENT UNDER
                          THE SECURITIES ACT OF 1933

                              PC CONNECTION, INC.
            (Exact name of registrant as specified in its charter)

               Delaware                                  02-0497006
      (State or other jurisdiction of                  (I.R.S. Employer
     incorporation or organization)                 Identification Number)

   528 Route 13, Milford, New Hampshire                      03055
   (Address of Principal Executive Offices)                (Zip Code)

        1993 Incentive and Non-Statutory Stock Option Plan, as amended
                           (Full title of the plan)

                                Patricia Gallup
                           Chairman of the Board and
                            Chief Executive Officer
                              PC Connection, Inc.
                                 528 Route 13
                         Milford, New Hampshire 03055
                    (Name and address of agent for service)

                                (603) 423-2000
         (Telephone number, including area code, of agent for service)


================================================================================

                        CALCULATION OF REGISTRATION FEE

================================================================================


<TABLE>
<CAPTION>


                                          Proposed maximum       Proposed maximum     Amount of
Title of securities    Amount to be      offering price per     aggregate offering   registration 
 to be registered       registered             share                  price              fee
- ---------------------------------------------------------------------------------------------------
<S>                    <C>               <C>                    <C>                  <C> 
 
Common Stock,           
$0.01 par value         1,245,450            $20.38(1)            $25,382,271(1)       $7,488 
===================================================================================================
</TABLE>


(1)  Estimated solely for the purpose of calculating the registration fee, and
     based upon the average of the high and low prices of the Common Stock on
     Nasdaq National Market on April 20, 1998 in accordance with Rules 457(c)
     and 457(h) of the Securities Act of 1933.
================================================================================

<PAGE>
 
PART I.  INFORMATION REQUIRED IN THE SECTION 10(a) PROSPECTUS

          The information required by Part I is included in documents sent or
given to participants in the Registrant's 1993 Incentive and Non-Statutory Stock
Option Plan, as amended pursuant to Rule 428(b)(1) of the Securities Act of
1933, as amended (the "Securities Act").


PART II.  INFORMATION REQUIRED IN THE REGISTRATION STATEMENT

Item 3.   Incorporation of Documents by Reference
          ---------------------------------------

          The following documents, which are filed with the Securities and
Exchange Commission (the "Commission"), are incorporated in this Registration
Statement by reference:

          (1) The Registrant's latest annual report filed pursuant to Section
     13(a) or 15(d) of the Securities Exchange Act of 1934, as amended (the
     "Exchange Act"), or the latest prospectus filed pursuant to Rule 424(b)
     under the Securities Act that contains audited financial statements for the
     Registrant's latest fiscal year for which such statements have been filed.

          (2) All other reports filed pursuant to Section 13(a) or 15(d) of the
     Exchange Act since the end of the fiscal year covered by the annual report
     or the prospectus referred to in (1) above.

          (3) The description of the common stock of the Registrant, $0.01 par
     value per share (the "Common Stock"), contained in the Registration
     Statement on Form 8-A filed under the Exchange Act, including any amendment
     or report filed for the purpose of updating such description.

     All documents subsequently filed by the Registrant pursuant to Sections
13(a), 13(c), 14 and 15(d) of the Exchange Act, prior to the filing of a post-
effective amendment which indicates that all shares of Common Stock offered
hereby have been sold or which deregisters all shares of Common Stock then
remaining unsold, shall be deemed to be incorporated by reference herein and to
be part hereof from the date of the filing of such documents.  Any statement
contained in a document incorporated or deemed to be incorporated by reference
herein shall be deemed to be modified or superseded for purposes of this
Registration Statement to the extent that a statement contained herein or in any
other subsequently filed document which also is or is deemed to be incorporated
by reference herein modifies or supersedes such statement.  Any statement so
modified or superseded shall not be deemed, except as so modified or superseded,
to constitute a part of this Registration Statement.

                                       2

<PAGE>
 
Item 4.   Description of Securities
          -------------------------

          Not applicable.

Item 5.   Interests of Named Experts and Counsel
          --------------------------------------

          The legality of the Common Stock being offered hereby will be passed
upon for the Registrant by Hale and Dorr LLP, Boston, Massachusetts.

Item 6.   Indemnification of Directors and Officers
          -----------------------------------------

          Section 145 of the Delaware General Corporation Law, as amended,
provides that a corporation may indemnify any person who was or is a party or is
threatened to be made a party to any threatened, pending or completed action,
suit or proceeding, whether civil, criminal, administrative or investigative
(other than an action by or in the right of the corporation) by reason of the
fact that he is or was a director, officer, employee or agent of the
corporation, or is or was serving at the request of the corporation as a
director, officer, employee or agent of another corporation, partnership, joint
venture, trust or other enterprise, against expenses (including attorneys'
fees), judgments, fines and amounts paid in settlement actually and reasonably
incurred by him in connection with such action, suit or proceeding if he acted
in good faith and in a manner he reasonably believed to be in or not opposed to
the best interests of the corporation, and, with respect to any criminal action
or proceeding, had no reasonable cause to believe his conduct was unlawful.
Section 145 further provides that a corporation similarly may indemnify any
person who was or is a party or is threatened to be made a party to any
threatened, pending or completed action or suit by or in the right of the
corporation to procure a judgment in its favor by reason of the fact that he is
or was a director, officer, employee or agent of the corporation, or is or was
serving at the request of the corporation as a director, officer, employee or
agent of another corporation, partnership, joint venture, trust or other
enterprise, against expenses (including attorneys' fees) actually and reasonably
incurred by him in connection with the defense or settlement of such action or
suit if he acted in good faith and in a manner he reasonably believed to be in
or not opposed to the best interests of the corporation, except that no
indemnification shall be made in respect of any claim, issue or matter as to
which such person shall have been adjudged to be liable to the corporation
unless and only to the extent that the Delaware Court of Chancery or the court
in which such action or suit was brought shall determine upon application that,
despite an adjudication of liability but in view of all the circumstances of the
case, such person is fairly and reasonably entitled to indemnity for such
expenses which the Court of Chancery or such other court shall deem proper.

     Article SEVENTH of the Registrant's Amended and Restated Certificate of
Incorporation (the "Certificate") provides that, except to the extent that the
General Corporation Law of Delaware prohibits the elimination or limitation of
liability of 

                                       3

<PAGE>
 
directors for breaches of fiduciary duty, no director of the Registrant shall be
personally liable to the Registrant of its stockholders for monetary damages for
any breach of fiduciary duty as a director, notwithstanding any provision of law
imposing such liability.

     Article EIGHTH of the Certificate provides that the Registrant shall
indemnify each person who was or is a party or is threatened to be made a party
to any threatened, pending or completed action, suit or proceeding, whether
civil, criminal, administrative or investigative (other than an action by or in
the right of the Registrant), by reason of his or her position (an
"Indemnitee"), or by reason of any action alleged to have been taken or omitted
in such capacity, against all expenses, judgments, fines and amounts paid in
settlement actually and reasonably incurred by him or her or on his or her
behalf in connection with such action, suit or proceeding and any appeal
therefrom, if he or she acted in good faith and in a manner he or she reasonably
believed to be in, or not opposed to, the best interests of the Registrant, and,
with respect to any criminal action or proceeding, had no reasonable cause to
believe his or her conduct was unlawful.

     Article EIGHTH of the Certificate provides that the Registrant shall
indemnify any Indemnitee who was or is a party or is threatened to be made a
party to any threatened, pending or completed action or suit by or in the right
of the Registrant to procure a judgment in its favor by reason of Indemnitee's
position or by reason of any action alleged to have been taken or omitted in
such capacity, against all expenses and, to the extent permitted by law amounts
paid in settlement actually and reasonably incurred by him or her on his or her
behalf in connection with such action, suit or proceeding, and any appeal
therefrom, if he or she acted in good faith and in a manner he or she reasonably
believed to be in, or not opposed to, the best interests of the Registrant.

     As permitted by Section 145, the Registrant has purchased a general
liability insurance policy which covers certain liabilities of directors and
officers of the Registrant arising out of claims based on acts or omissions in
their capacity as directors or officers and for which they are not indemnified
by the Registrant.

Item 7.   Exemption from Registration Claimed
          -----------------------------------

          Not applicable.

Item 8.   Exhibits
          --------

          The Exhibit Index immediately preceding the exhibits to this
Registration Statement is incorporated herein by reference.

                                       4

<PAGE>
 
Item 9.   Undertakings
          ------------

     1.   The Registrant hereby undertakes:

          (1) To file, during any period in which offers or sales are being 
     made, a post-effective amendment to this Registration Statement:

              (i)   To include any prospectus required by Section 10(a)(3) of 
          the Securities Act;

              (ii)  To reflect in the prospectus any facts or events arising
          after the effective date of the Registration Statement (or the most
          recent post-effective amendment thereof) which, individually or in the
          aggregate, represent a fundamental change in the information set forth
          in the Registration Statement. Notwithstanding the foregoing, any 
          increase or decrease in volume of securities offered (if the total
          dollar value of securities offered would not exceed that which was
          registered) and any deviation from the low or high end of the
          estimated maximum offering range may be reflected in the form of
          prospectus filed with the Commission pursuant to Rule 424(b) if, in
          the aggregate, the changes in volume and price represent no more than
          20 percent change in the maximum aggregate offering price set forth in
          the "Calculation of Registration Fee" table in the effective
          registration statement; and

              (iii) To include any material information with respect to the plan
          of distribution not previously disclosed in the Registration Statement
          or any material change to such information in the Registration
          Statement;

          provided, however, that paragraphs (i) and (ii) do not apply if the
          --------  -------
          information required to be included in a post-effective amendment by
          those paragraphs is contained in periodic reports filed with or
          furnished to the Commission by the Registrant pursuant to Section 13
          or 15(d) of the Exchange Act that are incorporated by reference in the
          Registration Statement.

          (2) That, for the purpose of determining any liability under the
     Securities Act, each such post-effective amendment shall be deemed to be a
     new Registration Statement relating to the securities offered therein, and
     the offering of such securities at that time shall be deemed to be the
     initial bona fide offering thereof.

          (3) To remove from registration by means of a post-effective amendment
     any of the securities being registered which remain unsold at the
     termination of the offering.

          2.   The undersigned Registrant hereby undertakes that, for purposes
of determining any liability under the Securities Act, each filing of the
Registrant's annual report pursuant to Section 13(a) or 15(d) of the Exchange
Act (and, where applicable, each filing of an employee benefit plan's annual
report pursuant to Section 15(d) of the Exchange Act) that is incorporated by
reference in the Registration Statement shall be deemed to be a new Registration
Statement relating to the 

                                       5

<PAGE>
 
securities offered therein, and the offering of such securities at that time
shall be deemed to be the initial bona fide offering thereof.

          3.   Insofar as indemnification for liabilities arising under the
Securities Act may be permitted to directors, officers and controlling persons
of the Registrant pursuant to the foregoing provisions, or otherwise, the
Registrant has been advised that in the opinion of the Commission such
indemnification is against public policy as expressed in the Securities Act and
is, therefore, unenforceable.  In the event that a claim for indemnification
against such liabilities (other than the payment by the Registrant of expenses
incurred or paid by a director, officer or controlling person of the Registrant
in the successful defense of any action, suit or proceeding) is asserted by such
director, officer or controlling person in connection with the securities being
registered, the Registrant will, unless in the opinion of its counsel the matter
has been settled by controlling precedent, submit to a court of appropriate
jurisdiction the question whether such indemnification by it is against public
policy as expressed in the Securities Act and will be governed by the final
adjudication of such issue.

                                       6

<PAGE>
 
                                   SIGNATURES

     Pursuant to the requirements of the Securities Act of 1933, the Registrant
certifies that it has reasonable grounds to believe that it meets all of the
requirements for filing on Form S-8 and has duly caused this Registration
Statement to be signed on its behalf by the undersigned, thereunto duly
authorized, in the City of Milford, New Hampshire, on the 23rd day of April,
1998.

 
                              PC CONNECTION, INC.


                              By      /s/Patricia Gallup
                                ---------------------------
                                    Patricia Gallup
                                    Chairman of the Board and
                                    Chief Executive Officer



                               POWER OF ATTORNEY

     We, the undersigned officers and directors of PC Connection, Inc. hereby
severally constitute Patricia Gallup, Wayne L. Wilson and Paul P. Brountas, and
each of them singly, our true and lawful attorneys with full power to them, and
each of them singly, to sign for us and in our names in the capacities indicated
below, the Registration Statement on Form S-8 filed herewith and any and all
subsequent amendments to said Registration Statement, and generally to do all
such things in our names and behalf in our capacities as officers and directors
to enable PC Connection, Inc. to comply with all requirements of the Securities
and Exchange Commission, hereby ratifying and confirming our signatures as they
may be signed by said attorneys, or any of them, to said Registration Statement
and any and all amendments thereto.

     Pursuant to the requirements of the Securities Act, this Registration
Statement has been signed below by the following persons in the capacities and
on the date indicated.

                                       7

<PAGE>
 
       Signature                    Title                          Date
       ---------                    -----                          ---- 
     
                            Chairman of the Board and Chief
 /s/ Patricia Gallup        Executive Officer                   April 23, 1998
- ------------------------    (principal executive officer)
Patricia Gallup
 
                            Chief Financial Officer             April 23, 1998
 /s/ Mark Gavin             (principal financial and
- ------------------------    accounting officer)       
Mark Gavin                                                
 
 
 
                            Vice Chairman of the Board          April 23, 1998
 /s/ David Hall
- ------------------------
David Hall
 
                            Director                            April 23, 1998
 /s/ David Beffa-Negrini
- ------------------------
David Beffa-Negrini
 
                            Director                            April 23, 1998
 /s/ Martin C. Murrer
- ------------------------
Martin C. Murrer
 
                            Director                            April 23, 1998
 /s/ Peter J. Baxter
- ------------------------
Peter J. Baxter

                                       8

<PAGE>
 
                                 Exhibit Index
                                 -------------


Exhibit
Number      Description
- ------      -----------

4.1(1)      Amended and Restated Certificate of Incorporation of the Registrant
4.2(2)      By-Laws of the Registrant
5.1         Opinion of Hale and Dorr LLP
23.1        Consent of Hale and Dorr LLP (included in Exhibit 5.1)
23.2        Consent of Deloitte & Touche LLP
24          Power of Attorney (included in the signature page of this 
            Registration Statement)


_______________________
(1)  Incorporated herein by reference to Exhibit 3.2 to the Registrant's
     Registration Statement on Form S-1 (File No. 333-41171).

(2)  Incorporated herein by reference to Exhibit 3.4 to the Registrant's
     Registration Statement on Form S-1 (File No. 333-41171).

                                       9





<PAGE>
 
                                                                     EXHIBIT 5.1

                               HALE AND DORR LLP
                              Counsellors At Law
                 60 State Street, Boston, Massachusetts  02109
                        617-526-6000 * FAX 617-526-5000


                                April 23, 1998


PC Connection, Inc.
528 Route 13
Milford, NH 03055

   Re:    1993 Incentive and Non-Statutory Stock Option Plan
          --------------------------------------------------

Ladies and Gentlemen:

   We have assisted in the preparation of a Registration Statement on Form S-8
(the "Registration Statement") to be filed with the Securities and Exchange
Commission under the Securities Act of 1933, as amended (the "Securities Act"),
relating to an aggregate of 1,245,450 shares of Common Stock, $0.01 par value
per share (the "Shares"), of PC Connection, Inc., a Delaware corporation (the
"Company"), issuable under the Company's 1993 Incentive and Non-Statutory Stock
Option Plan, as amended (the "Plan").

   We have examined the Amended and Restated Certificate of Incorporation of the
Company, and the By-Laws of the Company and originals, or copies certified to
our satisfaction, of all pertinent records of the meetings of the directors and
stockholders of the Company, the Registration Statement and such other documents
relating to the Company as we have deemed material for the purposes of this
opinion.

   In our examination of the foregoing documents, we have assumed the
genuineness
 of all signatures, the authenticity of all documents submitted to us
as originals, the conformity to original documents of all documents submitted to
us as copies, the authenticity of the originals of such latter documents and the
legal competence of all signatories to such documents.

   We assume that the appropriate action will be taken, prior to the offer and
sale of the Shares in accordance with the Plan, to register and qualify the
Shares for sale under all applicable state securities or "blue sky" laws.

   We express no opinion herein as to the laws of any state or jurisdiction
other than the Delaware General Corporation Law statute and the federal laws of
the United States of America.

<PAGE>
 
   Based upon and subject to the foregoing, we are of the opinion that the
Shares have been duly authorized for issuance and, when the Shares are issued
and paid for in accordance with the terms and conditions of the Plan, the Shares
will be validly issued, fully paid and nonassessable.

   It is understood that this opinion is to be used only in connection with the
offer and sale of the Shares while the Registration Statement is in effect.

   Please note that we are opining only as to the matters expressly set forth
herein, and no opinion should be inferred as to any other matters.

   We hereby consent to the filing of this opinion with the Commission as an
exhibit to the Registration Statement in accordance with the requirements of
Item 601(b)(5) of Regulation S-K under the Securities Act.  In giving such
consent, we do not hereby admit that we are in the category of persons whose
consent is required under Section 7 of the Securities Act or the rules and
regulations of the Commission.


                              Very truly yours,

 
                              /s/ HALE AND DORR LLP

                              HALE AND DORR LLP



<PAGE>
 
                                                   EXHIBIT 23.2


INDEPENDENT AUDITORS' CONSENT

We consent to the incorporation by reference in this Registration Statement of
PC Connection, Inc. (the "Company") on Form S-8 of our report dated February 4,
1998 on the financial statements of the Company and our report dated February
27, 1998 on the financial statement schedule of the Company for the year ended
December 31, 1997, appearing in Amendment No. 4 to Registration Statement No.
333-41171 on Form S-1 of the Company.


/s/ Deloitte & Touche LLP

Boston, Massachusetts
April 23, 1998